Breast Cancer Advice. Keep up to date with the latest information and treatment of breast cancer.
A Member of the Healthscout Network
 Printer Friendly  Send to a Friend

Genetic Code Cracked for Two Cancers

Ivanhoe Newswire

(Ivanhoe Newswire) -- Scientists at Johns Hopkins Kimmel Cancer Center in Baltimore say they have identified 200 mutated genes linked to breast and colon cancer. Most of the genes were not previously associated with tumor initiation, growth, spread or control.

Efforts to map cancer genes are happening in many labs across the country. Scientists hope it will lead to more successful detection and treatment strategies. The work is painstakingly slow and tedious.

Related Stories
Black Women's Genes May Spur Deadlier Breast Cancer
Breast Cancer Drugs Not One-Size-Fits-All
Digital Mammography Boosts Chances of Spotting Malignancies
Related Videos
Attacking Advanced Breast Cancer
Keep Ovarian Cancer At Bay
Easing Radiation Side Effects
Related Slides
Breast Cancer
Breast Self-Exam

The researchers at Johns Hopkins in Baltimore began with 11 samples each from breast and colon cancer patients. Within each tumor cell are billions of individual chemicals called nucleotides that pair together to make the genetic structure. Changes in these nucleotides can cause a normal cell to become a cancerous cell.

Researchers examined the DNA code of 13,000 genes by dividing them into overlapping sections. They fed the sequences through computer software that matches up normal sequences with those from tumor samples. In the end, the team of scientists combed through 465 million nucleotides to find 1,500 that differed from the normal code. Through further examination, they found the 200 genes that were significantly changed or mutated.

The authors report the mutated genes in breast and colon cancer were almost completely distinct, explaining why each type of cancer is a very different disease.

The goal is to use these findings to help create new cancer drugs, report the authors.

This article was reported by, who offers Medical Alerts by e-mail every day of the week. To subscribe, go to:

SOURCE: Science Express, published online on Sept. 7, 2006

Last updated 9/8/2006

Disclaimer: The information provided on this website is for educational purposes only and does not serve as a replacement for care provided by your own personal health care team. This website does not render or provide medical advice, and no individual should make any medical decisions or change their health behavior based on information provided here. All pertinent content provided on this website should be discussed with your personal physician to evaluate whether it has any relevance to or impact on your specific condition. Reliance on any information provided by this website is solely at your own risk.

Nov 14, 2006
New! For timely and trustworth health information, expert advice and much more, visit Breast Cancer Connection
Patient Guide
Health Videos
Health Encyclopedia
Health News Archive
Affiliate Information
HealthScout Network
Contact Us
Privacy Policy
Terms of Use

We subscribe to the HONcode principles of the Health On the Net Foundation
About The HealthScout Network Contact Us
Copyright 2001-2006 Choicemedia, Inc. All rights reserved.

Please visit our partner sites: